The Benefits Of Magnolia Officinalis Extract

What Is Magnolia Officinalis Extract?

Magnolia officinalis extract is a product extracted from the dried root bark, stem bark or branch bark of Magnolia officinalis, a plant of the genus Magnolia in the Magnoliaceae family. The main components are phenols, volatile oils, alkaloids, etc. It has the functions of drying dampness and eliminating phlegm, lowering Qi and eliminating fullness. For dampness stagnation injury, nausea, vomiting and diarrhea, stagnation of Qi due to food accumulation, abdominal distension and constipation, dyspnea and cough due to phlegm retention.

Pharmacological Effects:

1. Muscle Relaxation

The aqueous extract of Magnolia officinalis has a significant curare-like effect, and its alcohol extract can reduce grip strength, and has a strong inhibitory effect on spasms induced by strychnine, picrotoxin and other drugs.

2. CNS Inhibition

The ether extract of magnolia bark can reduce the spontaneous activity of mice, and resist the excitement caused by methamphetamine or apomorphine, and magnolol and isohonokiol also have significant central inhibitory effects. Magnolol can completely inhibit the spinal cord reflex in mice, and the ether extract 0.25-1g/kg can exhibit a central inhibitory effect that makes any reflex disappear.

3. Effects On The Digestive System

Magnolia officinalis 50% ethanol extract has a significant inhibitory effect on hydrochloric acid ethanol gastric mucosal ulcer, and one of its active ingredients is identified as honokiol and magnolol.

4. Antibacterial Effect

Magnolia decoction in vitro experiments have antibacterial effects on Gram-positive bacteria such as Staphylococcus, pneumococcus, and hemolytic streptococcus and Gram-negative bacteria such as Shigella, Salmonella typhi, Escherichia coli, and Bacillus subtilis. The antibacterial effect of 62 kinds of traditional Chinese medicine powders on Staphylococcus albus, Bacillus subtilis, Escherichia coli and Salmonella typhi was checked on the plate, especially Magnolia officinalis had the strongest effect. Tests have shown that magnolia bark also has a certain inhibitory effect on pathogenic skin fungi.

5. Exciting Smooth Muscle Effect

Magnolia decoction has excitatory effects on isolated intestine and bronchi of rabbits and bronchial smooth muscle of guinea pigs. Magnolia officinalis decoction concentration of 1:166 showed excitatory effect on isolated mouse intestine.

6. Anti-Tumor Effect

The three extract components of magnolia bark, lignans, magnolol, honokiol and monoterpene magnolol, are 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced Epstein - Antagonist of Barr virus early antigen (EBv-EA) activation. Magnolol and its hydroxymethyl derivatives have obvious inhibitory effect on secondary skin tumors in mice.

7. Antihypertensive Effect

When the dose of honokiline is lower than the muscle relaxant dose, it has obvious antihypertensive effect. This effect cannot be resisted by antihistamines, indicating that it is not caused by the release of histamine. ~15 minutes, intramuscular injection can last more than 1 hour. Magnolia officinalis tincture water-soluble matter has antihypertensive effect to anesthetized cats, rabbits intravenously or intramuscularly, and makes the heart rate faster.

8. Anti-Caries Effect

Magnolia officinalis extracts were tested against cariogenic pathogenic bacteria - Streptococcus mutans, and found to have efficient and rapid bactericidal effect.

9.Anti-Ulcer Effect

Magnolia officinalis 5% ethanol extract has a significant inhibitory effect on mucosal ulcers. Magnolol has inhibitory effects on Shay'S pyloric ligation, water immersion stress gastric ulcer, and duodenal spasm induced by histamine.

10. Antispasmodic Effect

Magnolia officinale ether extract can reduce the grip strength, and has a strong inhibitory effect on the spasm induced by drugs such as strychnine, picrotoxin, and pentazole.

In the field of medicine, magnolia bark extract is widely used to treat digestive system problems, such as gastrointestinal disorders, diarrhea, vomiting, etc.; it has anti-inflammatory effects and can be used to treat rheumatoid arthritis, skin inflammation and other diseases; at the same time, its antibacterial It also provides new ideas for the treatment of infectious diseases. In addition, magnolia bark extract also has various biological activities such as anti-tumor and immune regulation, and has a positive effect on tumor patients and immune system regulation.

In the field of health products, Magnolia officinalis extract is widely used in regulating gastrointestinal function, Antioxidant, beauty and beauty, etc. It can help improve the balance of intestinal flora, enhance digestion and absorption functions, and promote physical health; at the same time, its antioxidant effect helps delay aging and improve skin texture, and is widely used in anti-aging products; in addition, magnolia bark extract It can also regulate endocrine and improve sleep quality, which plays an important role in maintaining physical and mental health.

In the field of cosmetics, magnolia bark extract is often used for antioxidant, anti-inflammatory, anti-wrinkle and other functions. Its antioxidant capacity can reduce free radical damage and delay the skin aging process; its anti-inflammatory effect can soothe skin discomfort and reduce redness, swelling, itching and other symptoms; in addition, Magnolia officinalis extract also has the effect of shrinking pores, anti-wrinkle and tightening, and is known as It is widely used in skin care products and cosmetics.

In general, Magnolia officinalis extract, as a natural plant extract, has rich medicinal and health care functions and is widely used in medicine, health products, cosmetics and other fields. It not only originates from traditional Chinese medicine, but also meets modern people's consumer demand for natural, healthy and safe products. With people's increasing awareness of health and their pursuit of natural products, magnolia bark extract will play an increasingly important role in future development and make greater contributions to human health and beauty.