When is the best time to take Coenzyme Q10?

What is organic coenzyme q10?

Coenzyme Q10 (CoQ10), also known as Ubiquinone (UQ) and Coenzyme Q (CoQ), is a coenzyme present in all eukaryotes that perform aerobic respiration. Q represents the quinone group, and 10 represents the number of isoprene attached to its tail. Its structure is similar to vitamin K, vitamin E and plastoquinone.Suppliers of our Food Raw Materials.

Organic coenzyme Q10 is one of the substances participating in the electron transport chain and aerobic respiration in the mitochondria of eukaryotic cells. It is also the only non-Protein member of the electron transport chain. 95% of the energy in the human body is formed from this, so it is used in high energy requirements. More Coenzyme Q10 can be found in various organs (such as heart, liver, kidney, etc.).

Coenzyme Q10 can carry one or two electrons due to its three redox states, from high to low oxidation number: ubiquinone (Q), semiquinone (ubisemiquinone, Q-), and reduced ubiquinone. (ubiquinol, QH2). Apart from this, it is also an Antioxidant.It are also Health Product Raw Materials.

1. Heart disease

(1) Heart failure

The Q-SYMBIO study shows that patients taking Coenzyme Q10 have lower rates of major adverse cardiovascular events, cardiovascular mortality and all-cause mortality, and can improve NYHA cardiac function class.It are also health product raw materials.

Analysis of the "China Heart Failure Diagnosis and Treatment Guidelines 2018" points out: Myocardial cell energy metabolism disorders play a certain role in the occurrence and development of heart failure. For the drug treatment of chronic heart failure with reduced ejection fraction (HFrEF), the use of drugs to improve myocardial energy metabolism Drugs such as trimetazidine and coenzyme Q10 can improve patients' cardiomyocyte energy metabolism, symptoms and heart function, and improve their quality of life.

(2) Coronary heart disease

Studies have found that organic coenzyme Q10 content less than 60% can cause palpitation, chest tightness, and body fatigue. Less than 40% can lead to myocardial infarction, myocardial ischemia, and coronary heart disease. Less than 25% can cause the heart to stop beating or even sudden death.

However, current evidence does not support the routine use of coenzyme Q10 in patients with coronary heart disease. More research is necessary to fully determine the benefits of coenzyme Q10 in patients with coronary heart disease before incorporating coenzyme Q10 into guided drug therapy.

(3) Other heart-related effects

Organic coenzyme Q10 has insignificant effects on specific cardiovascular risk factors such as blood pressure, dyslipidemia, and glycemic control;
There is a small amount of evidence that CoQ10 may reduce the risk of certain complications from cardiac surgery and can be taken before surgery;
It has no value in treating cancer, but it may reduce the risk of heart damage from one type of cancer chemotherapy drug;
It has no definite effect on arrhythmias, especially malignant or potentially malignant arrhythmias such as premature ventricular contractions, atrial fibrillation, and ventricular tachycardia, and the patient benefit is not significant.

2. Nervous system diseases

(1) Migraine

Organic CoQ10 may treat and prevent migraines.
Studies have found that coenzyme Q10 deficiency is common in people with migraines, and that coenzyme Q10 supplementation can reduce the incidence by three times compared with those who do not take coenzyme Q10. A larger study found that 1,550 patients with low CoQ10 levels experienced less pain and fewer attacks when given CoQ10 treatment. Therefore, CoQ10 appears to not only treat migraines but also prevent them, according to American Neurology It is recommended by the American Academy of Medicine and the American Headache Society for the prevention and treatment of migraines, and the above conclusions are based on limited evidence.

(2) Parkinson's disease

Coenzyme Q10 does not help relieve symptoms in people with Parkinson`s disease.
Coenzyme Q10 does not improve symptoms in people with early-stage Parkinson's disease, even at higher-than-usual doses, a large U.S. study suggests.
A 2017 review of this study and several other smaller studies concluded that CoQ10 was not significantly helpful in relieving Parkinson's symptoms or slowing the progression of diseases such as amyotrophic lateral sclerosis, Down syndrome and Huntington's disease.

3. Other functions

(1) Regarding the side effects of statin-associated muscle symptoms, although the results of each study are different, the overall scientific evidence does not support the view that coenzyme Q10 can reduce statin-associated muscle symptoms (SAMS: Statin-Associated Muscle Symptoms);
The latest 2018 U.S. cholesterol guidelines and the Taiwan Society of Lipid and Atherosclerosis Statin Intolerance Expert Consensus Statement "Safety and Side Effects of Statins" state that muscle enzyme level testing is not routinely recommended while taking statins (COR: III, LOE: B-R), the effect of coenzyme Q10 on muscle symptoms and myopathy is uncertain, and it cannot be determined whether it can improve statin-related muscle symptoms (COR: III, LOE: C-LD);It are also health product raw materials.
(2) A study investigated the effect of Coenzyme Q10 on physical activity. Supplementing 1200 mg of Coenzyme Q10 every day for 60 days can reduce muscle oxidative stress after exercise. The possible mechanism is that Coenzyme Q10 is involved in energy production. Supplementing Coenzyme Q10 can Improves physical condition and energy and reduces fatigue by reducing oxidative stress in cells and improving mitochondrial function;
(3) Similarly, the antioxidant properties of Coenzyme Q10 help and may even reverse the age-related decline in egg and sperm quality and quantity, improve sperm quality, activity and concentration, and improve reproductive capacity;
(4) Organic Coenzyme Q10 can reduce damage from internal and external factors by increasing energy production in skin cells and promoting antioxidant protection. Applying Coenzyme Q10 directly to the skin has been shown to reduce sun oxidative damage caused by ultraviolet rays, reduce wrinkle depth and even skin occurrence of cancer. However, other studies in this area have produced mixed results;
(5) Research on anti-aging, improving immunity and resistance is limited, and no conclusions can be drawn.

Organic coenzyme Q10 is an important nutrient that has many positive effects on human health. It acts as an "energy producer" within cells and helps maintain the normal operation of body functions. Therefore, choosing the best time to take it can better exert the effect of Coenzyme Q10. Below I will detail when is the best time to take Coenzyme Q10, and discuss its reasonable dosage and potential precautions.It are Cosmetic raw materials.

Taking time:

1. Morning: Because Coenzyme Q10 aids in energy production within cells, taking it on an empty stomach in the morning may provide additional energy support, helping to increase energy and improve mental state.
2. After meals: If you are prone to stomach discomfort, you can choose to take Coenzyme Q10 after meals. At the same time, coenzyme Q10 is a fat-soluble substance, and ingesting it with fat may help its absorption.It are Food Additives.
3. Before and after exercise: Taking Coenzyme Q10 before and after exercise can help provide additional energy support, reduce fatigue after exercise, and help promote physical recovery and healthy exercise.
4. Before bed: Coenzyme Q10 is beneficial to cardiovascular health and helps regulate the redox balance in the body, so taking it before bed may help improve cardiovascular health and contribute to sleep quality.

Reasonable dosage:

General recommendations: The general daily supplement dosage of organic coenzyme Q10 is 30-200 mg. The specific dosage can be adjusted according to personal circumstances and doctor's recommendations.
Special groups: Pregnant women, lactating women, children and other special groups should consult a doctor before use to determine the appropriate dosage.

Precautions:

Interactions with Drugs: Organic Coenzyme Q10 may interact with certain drugs and affect their efficacy, so you should consult your doctor before taking Coenzyme Q10, especially patients who are receiving other medications.

Risk of overdose: Long-term or excessive use of Coenzyme Q10 may cause adverse reactions, so you should follow the dosage guidance on the product instructions and use it under the guidance of a doctor.

Product Selection: Choose Coenzyme Q10 products with reliable quality to ensure their purity and safety.

In general, organic coenzyme Q10 is an important nutrient, and choosing the right time to take it will help to better exert its effects. Before taking Coenzyme Q10, it is recommended to seek advice from your doctor or nutritionist to determine the dosage and timing that is best for you.