​Natural Sweetener - Glycyrrhizic Acid Powder

What is Glycyrrhizic Acid?

Glycyrrhizic Acid Powder is a common organic compound with a chemical formula of C42H62O16 and a molecular weight of 822.94. It belongs to diterpenoid glycyrrhizic acid compounds. Glycyrrhizic acid has a variety of biological activities and is widely used in traditional Chinese medicine, health care products and cosmetics.

Glycyrrhizic acid has a special sweet taste, its sweetness is about 250 times that of sugar, and the sodium salt of glycyrrhizic acid extracted from licorice has a sweet taste even in an aqueous solution diluted 4000 times. However, it is not suitable for some foods directly as a food sweetener. Generally, it can be used in combination with natural sugars such as sugar, glucose, sugar, or saccharin, glycine, propylene glycol, etc. to obtain a more delicious sweet taste.

There are many effects of glycyrrhizic acid, let's take a look at them separately:

1. Antioxidant and anti-inflammatory effects

Glycyrrhizic acid has antioxidant and anti-inflammatory effects, can reduce oxidative stress and inflammatory reactions in the body, reduce pathological damage of cells, and have a good protective effect on the liver, cardiovascular system and other organs. At the same time, it can also promote the improvement of the body's immune function.

2. Anti-tumor effect

Glycyrrhizic acid has anti-tumor and immunoregulatory effects, can regulate the apoptosis and proliferation of tumor cells, promote the immune function of the body, and have inhibitory and killing effects on various cancer cells.

3. Antiviral effect

Glycyrrhizic acid has a strong antiviral effect, can inhibit the replication and spread of the virus, and can also inhibit the inflammatory response caused by the virus, and has a good recovery effect on some viral diseases.

4. Improve stomach symptoms

Glycyrrhizic acid can stimulate mucus secretion, increase the mucus layer in the stomach, and protect the stomach. At the same time, it can also promote the peristalsis of the gastrointestinal tract, speed up the digestion of food, and improve the symptoms of gastrointestinal reactive diseases.

Production Method:

Glycyrrhizic acid extracted from the rhizome of leguminous plant Glycyrrhizauralen-sisfisch, made into ammonium salt and then hydrolyzed. Licorice is our annual herb, mainly produced in Inner Mongolia and Gansu. The roots and rhizomes of licorice mainly contain glycyrrhizin, which is the potassium and calcium salts of glycyrrhizic acid (Glycyrrhiz-icacid), which is the sweet component of licorice. The sweetness is about 50 times that of sucrose. Add water to the crushed licorice, heat it, extract it continuously in countercurrent, separate and remove the grass dregs and impurities, and obtain an aqueous solution. Evaporate, concentrate, add sulfuric acid pH2-3 under stirring. Let the precipitation stand, and remove the supernatant in Chemicalbook. The precipitate was washed with water to remove sulfate radicals, concentrated by heating, and boiled to make glycyrrhizic acid paste. Glycyrrhizic acid paste was crushed and extracted 2-3 times with 95% ethanol for 3 hours each time to obtain ethanol solution. After filtration, stir ammonia to pH 7-7.5. Then filter to obtain the crude product of triammonium glycyrrhizinate, which is refined with glacial acetic acid to obtain beige monoammonium glycyrrhizinate. Add monoammonium glycyrrhizinate into 5% sulfuric acid aqueous solution, stir and heat to near boiling, reflux and hydrolyze for 15 hours, filter and wash with water to obtain crude glycyrrhetinic acid. After recrystallization and decolorization, oxalenic acid with a content of more than 92% can be obtained. Based on licorice, the total yield is about 0.5%.

The main uses of glycyrrhizic acid powder in food are:

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